SPN-00900 - Bradley, Terrence
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Investigator:
Terrence Bradley
Email
Coordinator:
IRB: 20211051
SDG: Leukemia/heme
Disease Site(s): Other Hematopoietic
Sponsor: Geron
Enrolling Sites:
Sylvester
Title: Phase 1/1b Study to Evaluate the Safety, Pharmacokinetics, Pharmacodynamics and Clinical Activity of Imetelstat and in Combination with Ruxolitinib in Patients with Myelofibrosis.
Eligibility Criteria - NCT05371964 *This information has been extracted from " www.clinicaltrials.gov"
20220775 - Bradley Terrence
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Investigator:
Terrence Bradley
Email
Coordinator:
IRB: 20220775
SDG: Leukemia/heme
Disease Site(s): Other Hematopoietic
Sponsor: Sumitomo Dainippon Pharma Oncology
Enrolling Sites:
Deerfield
Gables
Plantation
Sylvester
UMHTitle: A Phase I/2, Open-label, Dose-escalation, Safety, Pharmacokinetic, and Pharmacodynamic Study of Oral TP-3654 in Patients with Intermediate or High-risk Primary or Secondary Myelofibrosis
Eligibility Criteria - NCT04176198 *This information has been extracted from " www.clinicaltrials.gov"
20220185 - Chandhok Namrata
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Investigator:
Namrata Chandhok
Email
Coordinator:
IRB: 20220185
SDG: Leukemia/heme
Disease Site(s): Other Hematopoietic
Sponsor: Syntrix Pharmaceuticals
Enrolling Sites:
Sylvester
UMHTitle: A Phase 1, Open-Label, Dose-Escalation with Expansion Study of SX-682 Alone and in Combination with Oral or Intravenous Decitabine in Subjects with Myelodysplastic Syndrome
Eligibility Criteria - NCT04245397 *This information has been extracted from " www.clinicaltrials.gov"
20231172 - Chandhok Namrata
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Investigator:
Namrata Chandhok
Email
Coordinator:
IRB: 20231172
SDG: Leukemia/heme
Disease Site(s): Leukemia, not otherwise specified
Sponsor: Ohio State University
Enrolling Sites:
Aventura
Deerfield
Gables
Hollywood
Kendall
Plantation
Sylvester
UMHTitle: A Randomized Double-Blind Placebo-Controlled Phase II Multi-Center Study of Inflammation Modification of Canakinumab to Prevent Leukemic Progression of Clonal Cytopenias of Unknown Significance (CCUS): IMPACT Study
Eligibility Criteria - NCT05641831 *This information has been extracted from " www.clinicaltrials.gov"
20231417 - Chandhok Namrata
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Investigator:
Namrata Chandhok
Email
Coordinator:
IRB: 20231417
SDG: Leukemia/heme
Disease Site(s): Leukemia, not otherwise specified
Sponsor: Cullinan Therapeutics
Enrolling Sites:
Deerfield
Gables
Hollywood
Kendall
Plantation
Sylvester
UMHTitle: A Phase 1, Open-label, Preliminary Pharmacokinetics (PK) and Safety Study of CLN-049 (An fms-like tyrosine kinase 3 FLT3 x cluster of differentiation 3 CD3 bispecific T cell engager) in Patients with Relapsed/Refractory Acute Myeloid Leukemia (AML) or Myelodysplastic Syndrome (MDS)
Eligibility Criteria - NCT05143996 *This information has been extracted from " www.clinicaltrials.gov"
20201503 - Sekeres Mikkael
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Investigator:
Mikkael Sekeres
Email
Coordinator:
IRB: 20201503
SDG: Leukemia/heme
Disease Site(s): Other Hematopoietic
Sponsor: SCCC
Enrolling Sites:
Cleveland Clinic Ohio
SylvesterTitle: A multicenter, Phase Ib/II study that combines Luspatercept and Lenalidomide (L2) in lower-risk, non-del(5q) MDS Patients
Eligibility Criteria - NCT04539236 *This information has been extracted from " www.clinicaltrials.gov"
20220383 - Sekeres Mikkael
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Investigator:
Mikkael Sekeres
Email
Coordinator:
IRB: 20220383
SDG: Leukemia/heme
Disease Site(s): Other Hematopoietic
Sponsor: Rigel Pharmaceuticals
Enrolling Sites:
Sylvester
UMHTitle: An Open-label, Phase 1b Study of R289, an IRAK1/4 Inhibitor, in Patients with Lower-risk Myelodysplastic Syndromes (LR MDS) Who are Relapsed/Refractory/Resistant to Prior Therapies
Eligibility Criteria - NCT05308264 *This information has been extracted from " www.clinicaltrials.gov"
20230058 - Sekeres Mikkael
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Investigator:
Mikkael Sekeres
Email
Coordinator:
IRB: 20230058
SDG: Leukemia/heme
Disease Site(s): Other Hematopoietic
Sponsor: Keros Therapeutics
Enrolling Sites:
Sylvester
Title: A Phase 2, Open-Label, Ascending Dose Study of KER-050 for the Treatment of Anemia in Patients with Very Low, Low, or Intermediate Risk Myelodysplastic Syndromes (MDS)
Eligibility Criteria - NCT04419649 *This information has been extracted from " www.clinicaltrials.gov"
20230812 - Traeger Lara
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Investigator:
Lara Traeger
Email
Coordinator:
IRB: 20230812
SDG: Leukemia/heme
Disease Site(s): Leukemia, not otherwise specified
Sponsor: MASSACHUSETTS GENERAL HOSPITAL
Enrolling Sites:
Sylvester
UMHTitle: Specialty Compared to Oncology Delivered Palliative Care for Patients with Acute Myeloid Leukemia - SCOPE Leukemia
Eligibility Criteria - NCT05237258 *This information has been extracted from " www.clinicaltrials.gov"
20230633 - Venugopal Sangeetha
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Investigator:
Sangeetha Venugopal
Email
Coordinator:
IRB: 20230633
SDG: Leukemia/heme
Disease Site(s): Myeloid and Monocytic Leukemia
Sponsor: Oryzon Genomics SA
Enrolling Sites:
Deerfield
Gables
Plantation
Sylvester
UMHTitle: An escalation/expansion, Open label, Multicenter study of iadademstat and gilteritinib in patients with Relapsed or Refractory Acute Myeloid Leukemia (R/R AML) with FMS-like tyrosine kinase mutation (FLT3 mut+): The FRIDA Study/ CL04-ORY-1001
Eligibility Criteria - NCT05546580 *This information has been extracted from " www.clinicaltrials.gov"
20230816 - Venugopal Sangeetha
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Investigator:
Sangeetha Venugopal
Email
Coordinator:
IRB: 20230816
SDG: Leukemia/heme
Disease Site(s): Myeloid and Monocytic Leukemia
Sponsor: ETCTN
Enrolling Sites:
Sylvester
UMHTitle: A Phase 1 Study of M3814 in combination with MEC in Patients with Relapsed or Refractory Acute Myeloid Leukemia
Eligibility Criteria - NCT03983824 *This information has been extracted from " www.clinicaltrials.gov"
20240189 - Venugopal Sangeetha
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Investigator:
Sangeetha Venugopal
Email
Coordinator:
IRB: 20240189
SDG: Leukemia/heme
Disease Site(s): Leukemia, not otherwise specified
Sponsor: ETCTN
Enrolling Sites:
Deerfield
Gables
Plantation
Sylvester
UMHTitle: A Phase 1b Study of Menin Inhibitor SNDX-5613 in Combination with Daunorubicin and Cytarabine in Newly Diagnosed Patients with Acute Myeloid Leukemia and NPM1 Mutated/FLT3 Wildtype with Higher-Risk Features or MLL/KMT2A Rearranged Disease.
Eligibility Criteria - NCT05886049 *This information has been extracted from " www.clinicaltrials.gov"
20190675 - Watts Justin
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Investigator:
Justin Watts
Email
Coordinator:
IRB: 20190675
SDG: Leukemia/heme
Disease Site(s): Leukemia, Other,Myeloid and Monocytic Leukemia
Sponsor: SCCC
Enrolling Sites:
Deerfield
Gables
Kendall
Plantation
Sylvester
UMHTitle: An Open-Label Phase 1b Study of NEROFE, a Novel Hormone-Peptide in Adult Patients with Advanced Myelodysplastic Syndrome (MDS) and Acute Myelogenous Leukemia (AML)
Eligibility Criteria - NCT04365179 *This information has been extracted from " www.clinicaltrials.gov"
INCB057643 - Watts, Justin
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Investigator:
Justin Watts
Email
Coordinator:
IRB: 20200314
SDG: Leukemia/heme
Disease Site(s): Other Hematopoietic
Sponsor: Incyte Corporation
Enrolling Sites:
Sylvester
UMHTitle: A Phase 1, Open-Label, Safety and Tolerability Study of INCB057643 in Participants With Myelofibrosis and Other Advanced Myeloid Neoplasms
Eligibility Criteria - NCT04279847 *This information has been extracted from " www.clinicaltrials.gov"
20211090 - Watts Justin
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Investigator:
Justin Watts
Email
Coordinator:
IRB: 20211090
SDG: Leukemia/heme
Disease Site(s): Leukemia, Other
Sponsor: Sumitomo Dainippon Pharma Oncology
Enrolling Sites:
Sylvester
UMHTitle: A Phase 1/2, Open-Label, Dose-Escalation, Dose-Expansion Study of DSP-5336 in Adult Acute Leukemia Patients With and Without Mixed Lineage Leukemia (MLL)-Rearrangement or Nucleophosmin 1 (NPM1) Mutation
Eligibility Criteria - NCT04988555 *This information has been extracted from " www.clinicaltrials.gov"
20211126 - Watts Justin
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Investigator:
Justin Watts
Email
Coordinator:
IRB: 20211126
SDG: Leukemia/heme
Disease Site(s): Myeloid and Monocytic Leukemia
Sponsor: Hanmi Pharmaceutical Co., Ltd
Enrolling Sites:
Sylvester
UMHTitle: A Phase 1/2, Open-label, Multicenter, Dose Escalation and Expansion Study of the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of HM43239 in Patients with Relapsed or Refractory Acute Myeloid Leukemia (AML)
Eligibility Criteria - NCT03850574 *This information has been extracted from " www.clinicaltrials.gov"
20230424 - Watts Justin
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Investigator:
Justin Watts
Email
Coordinator:
IRB: 20230424
SDG: Leukemia/heme
Disease Site(s): Myeloid and Monocytic Leukemia
Sponsor: POLARIS PHARMACEUTICALS
Enrolling Sites:
Sylvester
UMHTitle: Phase IA/B Combination Study of ADI-PEG 20, Venetoclax and Azacitidine in Patients with Acute Myeloid Leukemia (AML)
Eligibility Criteria - NCT05001828 *This information has been extracted from " www.clinicaltrials.gov"
20240426 - Watts Justin
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Investigator:
Justin Watts
Email
Coordinator:
IRB: 20240426
SDG: Leukemia/heme
Disease Site(s): Leukemia, not otherwise specified
Sponsor: Aptevo Therapeutics
Enrolling Sites:
Aventura
Coral Springs
Deerfield
Gables
Hollywood
Kendall
Plantation
Sylvester
UMHTitle: A Phase 1b/2 Open-Label Study of APVO436 in Combination with Venetoclax and Azacitidine in Patients with Newly Diagnosed Acute Myeloid Leukemia (AML)
Eligibility Criteria - NCT06634394 *This information has been extracted from " www.clinicaltrials.gov"
20240437 - Watts Justin
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Investigator:
Justin Watts
Email
Coordinator:
IRB: 20240437
SDG: Leukemia/heme
Disease Site(s): Leukemia, not otherwise specified
Sponsor: BlossomHill Therapeutics
Enrolling Sites:
Sylvester
UMHTitle: A Phase 1/1b Open-Label, Dose Escalation, First-in-Human Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Preliminary Anti-leukemic Activity of the Orally Available CDC-Like Kinase (CLK) Inhibitor, BH-30236, in Adults with Relapsed or Refractory Acute Myelogenous Leukemia (R/R AML) or Higher-Risk Myelodysplastic Syndrome (HR-MDS)
Eligibility Criteria - NCT06501196 *This information has been extracted from " www.clinicaltrials.gov"
20240844 - Watts Justin
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Investigator:
Justin Watts
Email
Coordinator:
IRB: 20240844
SDG: Leukemia/heme
Disease Site(s): Leukemia, Other
Sponsor: NCI
Enrolling Sites:
Deerfield
Gables
Kendall
Plantation
Sylvester
UMHTitle: A Phase 2 Study of Venetoclax in Relapsed Classic or Variant Hairy Cell Leukemia
Eligibility Criteria - NCT06311227 *This information has been extracted from " www.clinicaltrials.gov"